Memantine (aka Akatinol)

Mode of action - neuroprotection, antispastic, antiparkinsonian.
We supply Memantine pills produced by CanonPharma (Russia) - reliable manufacturer operating under the strict control of the russian authorities.
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Active substance : Memantine

Memantine is a noncompetitive antagonist of glutamate N-methyl-D-aspartate (NMDA) receptor, inhibits glutamatergic neurotransmission and progression of neurodegenerative processes, has neuromodulating effects.
Memantine promotes normalization of mental activity (it improves memory and ability to concentrate, reduces fatigue, symptoms of depression and so forth.) Corrects motor disorders.


  • Dementia (Alzheimer's type, vascular, mixed dementia of all degrees of severity)
  • >dysfunction of the central nervous system of mild to moderate severity (weakening of memory and ability to concentrate, loss of interest in activities, fatigue, limiting the ability to care for themselves)
  • Cerebral and spinal spastic syndrome (due to traumatic brain injury, multiple sclerosis, stroke)
  • Parkinson's disease, parkinsonism.

Limitations to the use: Epilepsy, hyperthyroidism, spasms (including history), myocardial infarction, heart failure, pregnancy, breast-feeding.


Memantine enhances the effect of barbiturates, neuroleptics, anticholinergics, levodopa, dopamine agonists receptor (bromocriptine, etc.), Amantadine. It may change the effect of dantrolene and baclofen.

Dosing and Administration

Memantine is taken during a meal. The mode set individually, treatment is recommended to start with the lowest effective dose. Adults: initial dose - 5 mg / day, if necessary dose can be increased weekly by 5 mg,
maintenance dose - 10-20 mg / day (up to 30-60 mg / day).
Patients with renal impairment should be administered in smaller doses.
Babies - 0.5 mg / kg / day or the rate of 1 drop per 1 kg of body weight.

!! please take a note, that product may be labeled in Russian and provided with instructions in Russian. if you need instructions in English - please add a comment in the order form.

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Memantine - Canon (Akatinol*)


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