Dexamethasone pillsDexamethasone is a glucocorticoid. It has anti-inflammatory, antiallergic, antishock, immunosuppressive action.
(aka Decadron, Dectancyl, Dexamonozon, Dexona, Dexasone, Diodex, Fortecortin)
Dexamethasone interacts with specific cytoplasmic receptors and forms a complex that penetrates the cell nucleus, induces depression or expression of mRNA on ribosomes changing the formation of proteins, including lipocortin mediating cellular effects.
Dexamethasone prevents the release of inflammatory mediators from eosinophils and mast cells. Dexamethasone stops the activity of hyaluronidase, collagenase and proteases, normalizes the function of the extracellular matrix of cartilage and bone. Dexamethasone reduces capillary permeability, stabilizes cell membranes, including lysosomal inhibits the release of cytokines (interleukins 1 and 2, gamma interferon) of lymphocytes and macrophages. Dexamethasone affects all phases of inflammation, anti-proliferative effect is due to inhibition of monocyte migration into the inflammatory focus and fibroblast proliferation. Dexamethasone causes the involution of lymphoid tissue and lymphopenia, which causes immunosuppression.
Antiallergic action of Dexamethasone is a consequence of inhibition of synthesis and secretion of mediators of allergy and reducing the number of basophils. Dexamethasone restores adrenoceptor sensitivity to catecholamines. Dexamethasone accelerates the catabolism of proteins and reduces their content in the plasma, decreases glucose utilization by peripheral tissues and gluconeogenesis in the liver increases. Dexamethasone stimulates the formation of enzyme protein in the liver, surfactant, fibrinogen, erythropoietin, lipomodulin.
Dexamethasone causes a redistribution of body fat (increases lipolysis of adipose tissue of limbs and the deposition of fat in the upper half of the body and face). Dexamethasone favors the formation of higher fatty acids and triglycerides. Decadron reduces absorption and increases excretion of calcium; delay sodium and water secretion of ACTH. Dexamethasone has anti-shock action.
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0.5mg x 56 tablets
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